St. Nicholas Cathedral in Kup’yans’k was built between 1848 and 1852 according to a design by Fyodor Danilov.

The city’s first wooden St. Nicholas Church stood from 1705 to 1824.

The new church was built with donations from the landowner Ananin and the parishioners.

In 1932, the dome and bell tower were demolished, and meat was sold in the church’s sanctuary.

Nevertheless, religious services resumed in the 1950s.

The temple grounds were damaged as a result of shelling by Russian forces on September 26, 2022.

As a result of the shelling, the Sunday school and the church store were destroyed by fire.